dieta da fertilidade

Referências Bibliográficas

CAPITULO 1 – “O que é necessário saber sobre a fertilidade”
- Blyth E. Guidelines for infertility counselling in different countries: Is there an emerging trend?
Hum Reprod. 2012 Jul;27(7):2046-57.
- Cambiaghi, AS. Fertilização: um ato de amor. São Paulo: Lavidapress, 2011.
- Doldi N, Persico P, Di Sebastiano F, Marsiglio E, De Santis L, Rabellotti E, et al. Pathologic
findings in hysteroscopy before in vitro fertilization-embryo transfer (IVF-ET).GynecolEndocrinol.
2005 Oct;21(4):235-7.
- Larsen U. Research on infertility: which definition should we use? FertilSteril. 2005;83:846.
- Scheffer B, Remohí, J, García-Velasco JA, Pellicer A, Simón C. Reprodução Humana Assistida.
São Paulo: Atheneu, 2003.
- Speroff L, Fritz M .Femaly Infertility. In: Speroff&Fritz . Clinical Gynecologic Endocrinology and Infertility. Philadelphia: Lippincott Williams & Wilkins,2005:p.1013.
- The Practice Committee of American Society for Reproductive Medicine. Definitions of infertility and recurrent pregnancy loss. FertilSteril. 2008 Nov;90(5 Suppl):S60.
- The Practice Committee of the American Society for Reproductive Medicine. Diagnostic evaluation of the infertile female: a committee opinion. FertilSteril. 2012 Aug;98(2):302-307.
- The Practice Committee of the American Society for Reproductive Medicine. Diagnostic evaluation
of the infertile male: a committee opinion. FertilSteril. 2012 Aug;98(2):294-301.
- The Practice Committee of the American Society for Reproductive Medicine. Endometriosis and infertility: a committee opinion. FertilSteril. 2012 Jun 15.
- World Health Organization, WHO laboratory manual for the examination and processing of
human semen. Geneva:WHO press, 2010.

CAPITULO 2 - “Como a alimentação pode interferir na fertilidade”
Infertilidade Feminina
- Hornstein MD, Gibbons WE. Optimizing natural fertility in couples planning pregnancy. UpTo- Date ( 2012.
- The ESHRE Capri Workshop Group. Nutrition and reproduction in women. Human Reproduction Update, 2006; 12(3): 193-207.
- Bunting L, Boivin J. Knowledge about risk factors, fertility myths and illusory benefits of healthy habits in young people. Human Reproduction, 2008; 23(8): 1858-1864.
- Souter I, Baltagi LM, Kuleta D, et al. Women, weight and fertility: The effect of body mass index on the outcome of superovulation/intrauterine insemination cycles. Fertil Steril, 2011;
- Nuthalapaty FS, Rouse DJ. The impact of obesity on fertility and pregnancy. UpToDate (www. 2012.
- Bellver J, Melo MAB, Bosch E, et al. Obesity and poor reproductive outcome: the potential role of the endometrium. Fertil Steril, 2007; 88(2):446-51.

- Bewer JC, Balen AH. The adverse effects of obesity on conception and implantation. Reproduction,
2010; 140: 347-364.
- Law DCG, Maclehose RF, Longnecker MP. Obesity and time to pregnancy. Human Reproduction,
2007; 22(2): 414-420.
- Obesity and Reproduction: an educational bulletin. Practice Committee, American Society for
Reproductive Medicine, 2008. Fertil Steril.
- Van der Steeg JW, Steures P, Eijkemans MJC, et al. Obesity affects spontaneous pregnancy
chances in subfertile, ovulatory women. Human Reproduction, 2008; 23(2): 324-328.
- Bohler et al. Adipose tissue and reproduction in women. Fertil Steril, 2010; 94(3)
- Freizinger M, Franko DL, Dacey M, et al. The prevalence of eating disorders in infertile women.
Fertil Steril, 2010; 93: 72-78.
- Dunker KLL, Alvarenga MS, Alves VPO. Transtornos alimentares e gestação – Uma revisão.
- Chen EC, Brzyski RG. Exercise and reproductive dysfunction. Fertil Steril, 1999; 71(1)
- Norman RJ, Noakes M, Wu R, Davies MJ, et al. Improving reproductive performance in overweight/
obese women with effective weight management. Hum Reprod Update 2004; 10(3): 267–
- Merhi, ZO. Weight loss by bariatric surgery and subsequent fertility. Maimonides Medical Center,
2006. Fertil Steril.
- Merhi, ZO. Impact of bariatric surgery on female reproduction. Fertil Steril, 2009; 92(5): 1501-8.
- Colombo O, Pinelli G, Comelli M, et al. Dietary intakes in infertile women a pilot study.
- Mochos S, Chan JL, Mantzoros CS. Leptin and reproduction: a review. Fertil Steril, 2002;
- Miller KK, Parulekar MS, Schoenfeld E, et al. Decreased leptin levels in nomal weight women
with Hypothalamic Amenorrhea: The effects of body composition and nutritional intake. J clin
Endocrionol Metab, 1998; 83: 2309-2312
- Kirchengast S, Huber J. Body composition characteristics and fat distribuition patterns in young
infertile women. Fertil Steril, 2004; 81: 539-44.
- Chavarro JE, Rich-Edwards JW, Rosner BA, et al. Diet and Lifestyle in prevention of ovulatory
disorder infertility. Obstet Gynecol 2007; 110: 1050-8
Infertilidade Masculina
- Wong WY, Thomas CM, Merkus JMWM, et al. Male factor subfertility: possible causes and
impact of nutritional factors. Fertil Steril, 200; 73: 435-42
- Homan GF, Davies M, Norman R. The impact of lifestyle factors on reproductive performance
in the general population and those undergoing infertility treatment: a review. Human Reproduction
Update, 2007; 13(3): 209-223
- ASRM Practice Committee. Optimizing natural fertility. Fertil Steril, 2008; 90: S1-6
- Braga DPAF, Halpern G, Figueira RCS, et al. Food intake and social habits in male patients and
its relationship to intracytoplasmic sperm injection outcomes. Fertil Steril, 2012;97:53–9.
- Sinclair S. Male Infertility: Nutritional and Environmental Considerations. Alternative Medicine
Review, 2000; 5: 28-38
- Agarwal A, Prabakaran SA. Oxidative stress and antioxidants in male infertility: a difficult balance.
Iranian Journal of Reproductive Medicine, 2005; 3: 1-8
- Makker K, Agarwal A, Sharma R. Oxidative stress and male infertility. Indian J Med Res, 2009;
129: 357-367
- Hammound AO, Gibson M, Peterson M, et al. Impact of male obesity on infertility: a critical
review of current literature. Fertil Steril, 2008; 90: 897-904
- Hammound AO, Wilde N, Gibson M, et al. Male obesity and alteration in sperm parameters.
Fertil Steril, 2008; 90: 2222-2225.

- Linus Pauling Institute(LPI) - Micronutrient Research for Optimum Health: http://lpi.oregonstate.
- Dawson EB, Harris WA, Teter MC, Powell LC. Effect of ascorbic acid supplementation on the
sperm quality of smokers. Fertil Steril 1992; 58: 1034-1039.
- Dawson EB, Harris WA, Rankin WE, et al. Effect of ascorbic acid on male fertility. Ann NY
Acad Sci 1987;498:312-323.
- Scott R, MacPherson A, Yates RW, et al. The effect of oral selenium supplementation on human
sperm motility. Br J Urol 1998;82:76-80.
- Littaru GP, Lambrechts P. Coenzyme Q10: multiple benefits in one ingredient. OCL 2011; 18
- Balercia G, Mosca F, Manttero F. Coenzyme Q10 supplementation in infertile men with idiopatic
asthenozoospermia: an open, uncontrolled pilot study. Fertil Steril, 2004; 81:93-8.
- Safarinejad MR. Efficacy of coenzyme Q 10 on Semen Parameters, Sperm Function and Reproductive
Hormones in infertile men. The Journal of Urology 2009; 182: 237-248
- Kumamoto Y, Maruta H, Ishigami J, et al. Clinical efficacy of mecobalamin in the treatment
of oligozoospermia–results of double-blind comparative clinical study. Hinyokika Kiyo
- Sandler B, Faragher B. Treatment of oligospermia with vitamin B-12. Infertility 1984;7:133-
- Cohen HK, Bleha J, Lam-Kruglick P. A prospective study of the effects of female and male caffeine
consumption on the reproductive endpoints of IVF and gamete intra-Fallopian transfer.
Human Reproduction, 2002; 17: 1746-1754
- Marshburn PB, Sloan CS, Hammond MG. Semen quality and association with coffee drinking,
cigarette smoking, and ethanol consumption. Fertil Steril, 1989; 52:162-165.
- Aitken RJ, Best F, Richardson DW, et al. Influence of caffeine on movement characteristics, fertilizing
capacity and ability to penetrate cervical mucus of human spermatozoa. J. Reprod. Fert. 1983;
67: 19-27
- Chavarro JE, Toth TL, Sadio SM, et al. Soy food and isoflavone intake in relation to semen quality
parameters among men from an infertility clinic. Human Reproduction, 2008; 23:2584-2590
- Beaton LK, McVeigh BL, Dillingham BL, et al. Soy protein isolates of varing isoflavone content
do not adversely affect semen quality in healthy young men. Fertil Steril, 2010; 94:1717-22.
- Curtis KM, Savitz DA, Arbuckle TE. Effects of Cigarette Smoking, Caffeine Consumption, and
Alcohol Intake on Fecundability. Am J Epidemiol, 1997; 146: 32-41.
- Mendiola J, Torres AM, Moreno-Grau JM. Food intake and its relationship with semen quality:
a case-control study. Fertil Steril, 2009; 91: 812-818
- Agarwal A, Prabakaran SA. Oxidative stress and antioxidants in male infertility: a difficult balance.
Iranian Journal of Reproductive Medicine, 2005; 3: 1-8
- Zini A, San Gabriel M, Baazeem A. Antioxidants and sperm DNA damage: a clinical perspective.
J Assist Reprod Genet, 2009; 26:427-432
- Lenzi A, Lombardo F, Sogrô P, et al. Use of carnitine therapy in selected cases of male factor
infertility: a double-blind crossover trial. Fertil Steril, 2003; 79: 292-300.
- The Nutrient Data Laboratory (NDL) - USDA›s (United States Department of Agriculture)
National Nutrient Database for Standard Reference:

CAPITULO 3 – “Dieta da fertilidade”
- Willet W C, Sacks F, Trichopoulou A, et al. Mediterranean Diet pyramid: a cultural model for
healthy eating. Am J Clin Nutr 1995; 61: 1402S-6S.

- Ferro-Luzzi A, Branca F. Mediterranean Diet, Italian-style: prototype of a healthy diet. Am J
Clin Nutr 1995; 61: 1338S-45S.
- Trichopoulou A, Costacou T, Barnia C, Trichopoulos D. Adherence to a Mediterranean Diet and
Survival in a Greek Population. N Eng J Med 2003; 348 (26): 2599-2608
- Sofi F, Cesari F, Abbate R, et al. Adherence to Mediterranean diet and health status: meta-analysis.
BMJ 2008; 337: a1344
- Sofi, Francesco. The Mediterranean diet revisited: evidence of its effectiveness grows. Current
Opinion in Cardiology 2009; 24: 442-446
- Trichopoulou, Antonia. Traditional Mediterranean diet and longevity in the elderly: a review.
Public Health Nutrition 2004; 7(7): 943-947
- Trichopoulou A, Orfanos P, Norat T, et al. Modified Mediterranean diet and survival: EPIC-
-elderly prospective cohort study. BMJ 2005; 10
- Tognon G, Rothenberg E, Eiben G, et al. Does the Mediterranean diet predict longevity in the
elderly? A Swedish perspective. Age (Dordr). 2011; 33(3): 439–450.
- Romanguera D, Norat T, Vergnaud A-C, et al. Mediterranean dietary patterns and prospective
weight change in participants of the EPIC-PANACEA project. Am J Clin Nutr 2010; 92: 912-21.
- Pitsavos C, Panagiotakos D B, Tzima N, et al. Adherence to the Mediterranean diet is associated
with total antioxidant capacity in healthy adults: the ATTICA study. Am J Clin Nutr 2005;
- Chavarro J E, Rich-Edwards J W, Rosner B A, Willet WC. Use of multivitamins, intake of B
vitamins and risk of ovulatory infertility. Fertil Steril. 2008; 89(3): 668-676
- Chavarro J E, Rich-Edwards J W, Rosner B A, Willet WC. Dietary fatty acid intakes and the risk
of ovulatory infertility. Am J Clin Nutr 2007; 85: 231-7
- Hally, Susan S. Nutrition in reproductive health. Journal of Nurse-Midwifery 1998; 43(6): 459-470
- Vujkovic M, Vries J H, Lindemans J, et al. The preconception Mediterranean dietary pattern in
couples undergoing in vitro fertilization/intracytoplasmatic sperm injection treatment increases
the chance of pregnancy. Fertil Steril 2010, 94(6): 2096-2101
- Gardiner P M, Nelson L, Shellhaas C S, et al. The clinical content of preconception care: nutrition
and dietary supplements. American Journal of Obstetrics – Gynecology 2008; 10: S345-356.
- Twigt JM, Bolhuis MEC, Steegers EAP, et al. The preconception diet is associated with the chance
of ongoing pregnancy in women undergoing IVF/ICSI treatment. Human Reproduction
2012, 0(0): 1-6
- Moos M-K, Dunlop A L, Jack B W, et al. Healthier women, healthier reproductive outcomes:
recommendations for the routine care of all women of reproductive age. American Journal of
Obstetrics – Gynecology 2008; 10: S280-289.
- Northstone K, Emmett P, Rogers I. Dietary patterns in pregnancy and associations with socio-
-demographic and lifestyle factors. Eur J Vlin Nutr 2008; 62(4): 471-479
- Nicola, Alessandro. Portal Mediterrâneo: o azeite nas culinárias espanhola e marroquina. LMA
Editora e Distribuidora Ltda, São Paulo, 2011. 1° edição.
- Parker, Steve. The Advanced Mediterranean Diet: lose weight, feel better, live longer. pxHealth,
2nd editon. 2012
- Lucchese F, Machado J A P. Dieta mediterrânea: com sabor brasileiro. L&PM, 7 ed. , 2010.
- Groll, Jeremy and Lorie. Fertility Foods. Fireside, 2006.
- Shannon, Marilyn M. Fertility, Cycles and Nutrition: Can what you eat affect your menstrual
cycles and your fertility? The Couple to Couple League, 3rd ed, 2001.
- Chavarro J E, Willet W C. The fertility diet: groundbreaking research reveals natural ways to
boost ovulation and improve your chances of getting pregnant. McGraw-Hill 2007.
- Reiss, Fern. The Infertility Diet: Get pregnant and prevent miscarriage. Peanut Butter and Jelly
Press, 2004 Edition.

CAPITULO 4 – “Endometriose”
- James MJ, Gibson RA e Cleland LG. Dietary polyunsaturated fatty acids and inflammatory mediator
production. Am J Clin Nutr 2000; 71: 343S-8S
- Gazvani MR, Smith L, Haggarty, et al. Fatty acids and in vitro endometrial cell survival. Fertil
Steril 2001; 76(4): 717-22
- Netsu S, Konno R, Odagiri K, et al. Oral eicosapentaenoic acid supplementation as possible therapy
for endometriosis. Fertil Steril 2008; 90(2): 1496-1502
- Bellelis P, Podgaec S, Abrão MS. Fatores ambientais e endometrioses. Rev.. Assoc Med Bras 2011;
- Fontenele EGP, Martins MRA, Quidute ARP, et al. Contaminantes ambientais e os interferentes
endócrinos. Arq Bras Endocrinol Metab. 2010; 54/1
- The Practice Committee of the American Society for Reproductive Medicine. Status of environment
and dietary estrogens – are they significant estrogens? Fertil Steril 2004; 82(1): S166-68
- Szczepanska M, Kozlik J, et al. Oxidative stress may be a piece in the endometriosis puzzle. Fertil
Steril 2003; 79(6): 1288-93
- Savaris AL, do Amaral VF. Avaliação do perfil Nutricional e a capacidade antioxidante de mulheres
com endometriose pélvica. Dissertação de Mestrado apresentada ao Programa de Pós-
-graduação em Ciências Ambientais e Saúde, da Pró
- Reitoria de Pós-Graduação e Pesquisa da Universidade Católica de Goiás, como requisito parcial
para obtenção do título de Mestre em Ciências Ambientais e Saúde. 2010.
- Bianchi MLP, Antunes LMG. Radicais livres e os principais antioxidantes da dieta. Rev. Nutr,
1999; 12(2): 123-130
- Mier-Cabrera J, Aburto-Soto T, Burrola-Méndez S, et al. Women with endometriosis improved
their peripheral antioxidant markers after the application of a high antioxidant diet. Reproductive
Biology and Endocrinology 2009, 7:54
- Ballweg ML. Endometriosis: the complete reference for taking charge of your health. McGraw-
-Hill 2003
- Panth M, et al. Effects of Vitamin A supplementation on plasma progesterone and estradiol
levels during pregnancy. Int J Vit Nutr Res: 61; 1991
- Bruner-Tran KL, Osteen KG, Taylor HS, et al. Resveratrol inhibits development of experimental
endometriosis in vivo and reduces endometrial stromal cell invasiveness in vitro(Resveratrol
inhibits experimental endometriosis). BOR Papers in Press, The Society for the Study of Reproduction,
- Parazzini F, Chiaffarino F, Surace M, et al. Selected food intake and risk of endometriosis. Human
Reproduction 2004; 19(8): 1755-59.
- Wenzl R, Ott J, Huber J. A Mediterranean diet decreases endometriosis – associated pain: A prospective
cohort study. Presented 2011 World Symposium on Endometriosis. Atlanta, Georgia
- Hofmekler O. The anti-estrogenic diet. North Atlantic Books (P.41 – 77)
- Missmer AS, Chavarro JE, Malspeis S, et al. A prospective study of dietary fat consumption and
endometriosis risk. Human Reproduction 2010; 25(6): 1528-35
- Osteen KG, Bruner-Tran KL, Eisenberg E. Reduced progesterone action during endometrial
maturation: a potential risk factor for the development of endometriosis. Fertil Steril 2005; 83(3):
- Bruner-Tran KL, Rier SE, Eisenberg E, Osteen KG. The potential role of environmental toxins
in the pathophysiology of endometriosis. Gynecol Obstet Invest. 1999;48(1):45-56.
- Wieser F, Cohen M, Gaeddert A, et al. Evolution of medical treatment for endometriosis: back to
the roots?. Human Reproduction Update, 2007; 13(5): 487:499
- Han KK, Soares Junior JM, Haidar MA, et al. Efeitos dos fitoestrogênios sobre alguns parâmetros
clínicos e laboratoriais no climatério. RBGO, 2002. 24(8): 547-552
- Rose DP, Goldman M, Connolly JM, et al. High-fiber diet reduces serum estrogen concentrations
in premenopausal women. Am J Clin Nutr 1991; 54: 520-5
- Barnard N. Foods that fight pain: Revolutionary new strategies for maximum pain relief. Three
rivers press, New York 1998.
- Levett, Carolyn. Recipes for the endometriosis diet: A comprehensive diet resource for the women
with Endometriosis. Endo Resolved, 2008.

CAPITULO 5 – “Síndrome dos ovários policísticos (SOP)”
- Azevedo GD, Costa EC, Barbosa MTA, et al. Modificações do estilo de vida na síndrome dos
ovários policísticos: papel do exercício físico e importância da abordagem multidisciplinar. Ver
Bras Ginecol Obstet.2008; 30(5)261-7.
- Cerqueira JMC, Costa LOBF, Nogueira AAV, et al. Homocisteinemia em mulheres com síndrome
dos ovários policísticos. Ver Bras Ginecol Obstet. 2010; 32(3): 126-32.
- Chavarro JE, Willet WC. The Fertility Diet. Mc Graw Hill. 2007; 22-26.
- Gambineri A, Pelusi C, Vicennati V, et al. Review: Obesity and the polycystic ovary syndrome.
International Journal of Obesity 2002. 26; 883-896.
- Kasim-Karakas SE, Cunningham WM, Tsodikov A. Relation of nutrients and hormones in
polycystic ovary syndrome. Am J Clin Nutr 2007; 85: 688-94.
- Kuba VM, Cavalini PM, Christóforo AC, et al. Resistência Insulínica e Perfil Metabólico em Pacientes
com Síndrome dos Ovários Policísticos de Peso Normal e Sobrepeso/Obesidade. Arq
Bras Endocrinol Metab 2006; 50(6): 1026-1033.
- Legro RS, Myers ER, Barnhart HX, et al. The Pregnancy in Polycystic Ovary Syndrome Study:
baseline characteristics of the randomized cohort including racial effects. Fertil Steril 2006; 86:
- Moraes LAM, Maciel GAR, Silva de Sá MF, et al. Síndrome dos Ovários Policisticos. Federação
Brasileira das Sociedades de Ginecologia e Obstetrícia, Projeto Diretrizes, Associação Médica
Brasileira e Conselho Federal de Medicina, 2002.
- Moran LJ, Noakes M, Clifton PM, et al. Dietary Composition in Restoring Reproductive and
Metabolic Physiology in Overweight Women with Polycystic Ovary Syndrome. J Clin Endocrinol
Metab, 2003; 88(2):812–819.
- Moran LJ, Pasquali R, Teede H, et al. Treatment of obesity in polycstic ovary syndrome: a position
statement of the Androgen Excess and Polycystic Ovary Syndrome Society. Fertil Steril
2009; 92: 1966-82.
- Premoli ACG, de Moura MD, Ferriani RA, et al. Perfil Lipidico em Pacientes Portadoras da Síndrome
de Ovários Policísticos. Rev Bras Ginecol Obstet. 2000; 22(2): 89-94.
- Thomson RL, Buckley JD, Lim SS, et al. Lifestyle management improves quality of life and depression
in overweight and obese women with polycystic ovary syndrome. Fertil Steril 2010; 94: 1812-6.
- Whright, Hillary. The PCOS Diet Plan: A Natural approach to Health for women with polycystic
ovary syndrome. Celestial Arts 2010.
- Yarak S, E Bagatin, Hassun KM, et al. Hiperandrogenismo e pele: síndrome do ovário policístico
e resistência periférica à insulina. An Bras Dermatol. 2005; 80(4):395-410.

CAPITULO 6 – “Abortos”
- Metwally M, Ong KJ, Ledger WL, Li TC. Does high body mass index increase the risk of miscarriage
after spontaneous and assisted conception? A meta-analysis of the evidence. Fertil Steril.
- Tulandi T, Al-Fozan HM. Spontaneous abortion: risk factors, etiology, clinical manifestations, and
diagnostic evaluation. UpToDate ( 2012.
- Ronnenberg AG, Venners S A, Xiping X, et al. Preconception B-Vitamin and Homocysteine Status,
Conception, and Early Pregnancy Loss. Am J Epidemiol 2007; 166:304-312.
- Neves LB et al. Homocisteína. Bras Patol Med Lab 2004, v.40 n.5:311-20.
- Vujkovic M, Vries JH, Lindemans J, et al. The preconception Mediterranean dietary pattern in
couples undergoing in vitro fertilization/intracytoplasmatic sperm injection treatment increases
the chance of pregnancy. Fertil Steril 2010; 94(6): 2096-2101
- Mistry HD, Williams PJ. Review article: The importance of Antioxidant Micronutrients in
Pregnancy. Oxidative Medicine and Cellular Longevity 2011, n° artigo 841749.
- Santos LMP, Pereira ZP. Efeito da fortificação com ácido fólico na redução dos defeitos do tubo
neural. Cad. Saúde Pública 2007, 23(1): 17-24
- Nasser C, Nobre C, Mesquita S, et AL. Semana da Conscientização sobre a importância do acido
fólico. J Epilepsy Clin Neurophysiol 2005; 11(4): 199-203
- Saunders C, Padilha P, Gomes MM, et al. A influencia de características maternas e historia de
abortamento no resultado obstétrico. Nutrire: rev. Soc. Bras. Alim. Nutr = Brazilian Soc. Food
Nutr. 2009, v. 34, n.1, p1-11.
- Rumbold A, Middleton P, Pan N, Crowther CA. Vitamin supplementation for preventing miscarriage.
Cochrane Database of Systematic Reviews 2011, ed. 1, n° artigo CD004073.
- Bulletti C, Flamigni C, Giacomucci E. Reproductive failure due to spontaneous abortion and
recurrent miscarriage. Hum Reprod Update. 1996 Mar-Apr;2(2):118-36.
- Chan YY, Jayaprakasan K, Zamora J, Thornton JG, Raine-Fenning N, Coomarasamy A.The prevalence
of congenital uterine anomalies in unselected and high-risk populations: a systematic
review. Hum Reprod Update. 2011 Nov-Dec;17(6):761-71. Epub 2011 Jun 24.
- de la Rochebrochard E, Thonneau P. Paternal age and maternal age are risk factors for miscarriage;
results of a multicentre European study. Hum Reprod. 2002 Jun;17(6):1649
- Kalousek DK, Pantzar T, Tsai M, Paradice B. Early spontaneous abortion: morphologic and karyotypic
findings in 3,912 cases. Birth Defects Orig Artic Ser. 1993;29(1):53-61.
- Kesmodel U, Wisborg K, Olsen SF, Henriksen TB, Secher NJ.Moderate alcohol intake in pregnancy
and the risk of spontaneous abortion. Alcohol Alcohol. 2002 Jan-Feb;37(1):87-92

CAPITULO 7 – “Preparando-se para a gestação”
- American College of Obstetricians and Gynecologists. ACOG Committee Opinion (Immunization
during pregnancy). Obstet Gynecol. 2003;101:207–212
- Australia New Zealand Food Authority. (1998). [Folate: Make it part of your day].
- Cederberg J, Simán CM, Eriksson UJ. Combined treatment with vitamin E and vitamin C decreases
oxidative stress and improves fetal outcome in experimental diabetic pregnancy. Pediatr Res.
2001 Jun;49(6):755-62.
- Chaves Netto, Hermógenes. Obstetrícia básica. Capítulo 16, páginas 167 a 178; Chaves Netto, H;
Sá, R.A.M., 1ª edição, 2004.
- Gilles R, Monif G, Baker DA. Infectious diseases in obstetrics and gynecology. 5th ed.. United
Kingdom: Taylor and Francis; 2004;
- Gonik B, Fasano N, Foster S. The obstetrician-gynecologist’s role in adult immunization. Am J
Obstet Gynecol. 2002;187:984–988
- Munoz FM, Englund JA. Vaccines in pregnancy. Infect Dis Clin North Am. 2001;15:253–271
- Naish, F. and Roberts, J. (2000) The Natural Way to Better Babies. Random House: Sydney.
- Nogueira S.A., Reis M.A.B., Lambert J.S. Manual para diagnóstico e tratamento de infecções na
gravidez, páginas 102 a 109; Martins, R.M., 1ª edição, 2000
- Ogle, A. (1998). Before your pregnancy: Prepare your body for a health
- Ogle, A. (1999). [12 tips to follow before conceiving a baby]. ParenthoodWeb - Osrin D, de L Costello AM. Maternal nutrition and fetal growth: practical issues in international
health. Semin Neonatol. 2000 Aug;5(3):209-19.
- SBIM&FEBRASGO, Vacinação da Mulher, consenso 2010-2011
- Schrag SJ, Fiore AE, Gonik B, Malik T, et al. Vaccination and perinatal infection prevention practices
among obstetrician-gynecologists. Obstet Gynecol. 2003;101:704–710
- The Practice Committee of the American Society for Reproductive Medicine; Vaccination guidelines
for female infertility patients , Fertility and Sterility ,Volume 86, Issue 5, Supplement, Pages
S28-S30, November 2006
- Verma RJ, Sherlin DM. Vitamin C ameliorates fluoride-induced embryotoxicity in pregnant rats.
Hum Exp Toxicol. 2001 Dec;20(12):619-23.

CAPITULO 8 – “Alimentação durante a gestação”
- Parizzi M R, Fonseca J G M. Nutrição na gravidez e na lactação. Ver Med Minas Gerais, 2010;
20(3): 341-353
- Gillen-Goldstein J, Funai E, Roque H, Ruvel J M. Nutrition in pregnancy. UpToDate (www. 2012.
- Nascimento E, Souza S B. Avaliação da dieta de gestantes com sobrepeso. Rev. Nutr. Campinas,
2002; 15(2): 173-179.
- Arkkola, Tuula. Diet during pregnancy: Dietary patterns and weight gain rate among finish
pregnant women. Acta Univ. Oul. D 1037, 2009, Finland.
- Dal Bosco, Simone Morelo. Nutrição da mulher: uma abordagem nutricional da saúde a doença.
Editora Metha, 2010.
- Freitas E S, Dal Bosco S M, Sippel C A, Lazzaretti R K. Recomendações nutricionais na gestação.
- Oliveira, Flávio Garcia. Receitas para grávidas. Idéia e ação, 2008.
- Chasen S T, Chervenack F A. Twin Pregnancy: Prenatal issues. UpToDate (
- Werutsky N M A, Frangella V S, Pracanica D, et al. Avaliação e recomendações nutricionais
específicas para a gestante e puérpera gemelar. Einstein, 2008; 6(2):212-220.
- Keith L G, Blickstein I. Triplet pregnancies and their consequences. The Parthenon Publishing
Group, 2002.
- Philipson, Elliot H. Nutrition in Multifetal Pregnancy. Nutrition and Health: Handbook of Nutrition
and Pregnancy. Humana Press, 2008. Chapter 7, p. 93-100.
- Luke, Barbara. Nutrition and Multiple Gestation. Elsevier Inc. Semin Perinatol, 2005; 29:
- Luke, Barbara. Improving Multiple pregnancy interventions. Clinical Obstetrics and gynecology
, 2004; 47: 146-162
- Dubois S, Dougherty C, Duequette MP, et al. Twin pregnancy: the impact of the Higgins
Nutrition Intervention Program on maternal and neonatal outcomes. Am J Clin Nut 1991; 53:
- My Pyramid – USDA (2007) – My Pyramid in action: Tips for pregnant moms
- Roselló-Soberón M E, Fuentes-Chaparro L, Casanueva E. Nutritions Reviews, 2005; 63(9):
- Cambiaghi, Arnaldo Schizzi. Grávida Feliz, obstetra feliz: guia de orientações para o casal grávido.
Editora La vida Press, 2008.

CAPITULO 9 – “A fertilidade pode ser preservada”
- Sonmezer M, Oktay K. Fertility preservation in female patients. Hum Reprod Update
- Lawson CC, Schnorr TM, Daston GP, Grajewski B, Marcus M, McDiarmid M, et al. An occupational
reproductive research agenda for the third millennium. Environ Health Perspect
- Heindel JJ. Role of exposure to environmental chemicals in the developmental basis of reproductive
disease and dysfunction. Semin Reprod Med 2006;24:168–77.
- Kim SS. Fertility preservation in female cancer patients: current developments and future directions.
Fertil Steril 2006;85:1–11.
- Su HI, Lin K, Bracia CR. Early menopause in cancer survivors: fertility options. Menopausal Med
- Garner E, Goldstein DP, Berkowitz RS, Wenzel L. Psychosocial and reproductive outcomes of
gestational trophoblastic diseases. Best Pract Res Clin Obstet Gynaecol 2003;17:959–68.
- Maltaris T, Koelbl H, Seufert R, Kiesewetter F, Beckmann MW, Mueller A, et al. Gonadal damage
and options for fertility preservation in female and male cancer survivors. Asian J Androl
2006;8: 515–33.
- Lee SJ, Schover LR, Partridge AH, Patrizio P, Wallace WH, Hagerty K, et al. American Society
of Clinical Oncology recommendations on fertility preservation in cancer patients. J Clin Oncol
- Sonmezer M, Oktay K. Fertility preservation in female patients. Hum Reprod Update
- Heindel JJ. Role of exposure to environmental chemicals in the developmental basis of reproductive
disease and dysfunction. Semin Reprod Med 2006;24:168–77.
- Stillman RJ, ed. Seminars in reproductive endocrinology: smoking and reproductive health. New
York: Thieme Medical Publishers, 1989.
- Weisberg E. Smoking and reproductive health. Clin Reprod Fertil 1985;3:175–86.
- Stillman RJ, Rosenberg MJ, Sachs BP. Smoking and reproduction. Fertil Steril 1986;46:545–66.
- Fredricsson B, Gilljam H. Smoking and reproduction. Short and long term effects and benefits of
smoking cessation. Acta Obstet Gynecol Scand 1992;71:580–92.
- Lobo RA. Potential option for preservation of fertility in women. N Engl J Med 2005;353:64–73.
- Donnez J, Martinez-Madrid B, Jadoul P, Van Langendonckt A, Demylle D, Dolmans MM. Ovarian
tissue cryopreservation and transplantation: a review. Hum Reprod Update 2006;12:519–35.
- Gook DA, Schiewe MC, Osborn SM, Asch RH, Jansen RP, Johnston WI. Intracytoplasmic sperm
injection and embryo development of human oocytes cryopreserved using 1,2-propanediol. Hum
Reprod 1995;10:2637–41.
- Porcu E, Fabbri R, Damiano G, Giunchi S, Fratto R, Ciotti PM, et al. Clinical experience and
applications of oocyte cryopreservation. Mol Cell Endocrinol 2000;169:33–7.
CAPITULO 10 – “Quando a boa alimentação não é o bastante”
- Bartmann AK, Romao GS, Ramos Eda S, Ferriani RA. Why do older women have poor implantation
rates? A possible role of the mitochondria. J Assist Reprod Genet 2004;21:79–83.
- Cobo A, Diaz C.Clinical application of oocyte vitrification: a systematic review and meta-analysis
of randomized controlled trials.FertilSteril. 2011 Aug;96(2):277-85.
- Cobo A, Meseguer M, Remohí J, Pellicer A. Use of cryo-banked oocytes in an ovum donation
programme: a prospective, randomized, controlled, clinical trial. Hum Reprod. 2010

- Heffner LJ.Advanced maternal age--how old is too old? N Engl J Med. 2004 Nov 4;351(19):1927-9.
- Khalil MR, Rasmussen PE, Erb K, Laursen SB, Rex S, Westergaard LG. Homologous intrauterine
insemination. An evaluation of prognostic factors based on a review of 2473 cycles.ActaObstetGynecol
Scand. 2001 Jan;80(1):74-81.
- Leridon H. Can assistedreproduction technology compensate for the natural decline in fertility
with age? A model assessment. Hum Reprod. 2004 Jul;19(7):1548-53.
- Scheffer B, Remohí, J, García-Velasco JA, Pellicer A, Simón C. Reprodução Humana Assistida.
São Paulo: Atheneu, 2003.
- Sher G, Keskintepe L, Keskintepe M, Maassarani G, Tortoriello D, Brody S.Genetic analysis of
human embryos by metaphase comparative genomic hybridization (mCGH) improves efficiency
of IVF by increasing embryo implantation rate and reducing multiple pregnancies and spontaneous
miscarriages.FertilSteril. 2009 Dec;92(6):1886-94.
- Stoop D, Vercammen L, Polyzos NP, de Vos M, Nekkebroeck J, Devroey P.Effect of ovarian
stimulation and oocyte retrieval on reproductive outcome in oocyte donors.FertilSteril. 2012
- van der Linden M, Buckingham K, Farquhar C, Kremer JA, Metwally MLutealphasesupport for
assistedreproductioncycles. Cochrane DatabaseSyst Rev.2011 Oct 5;(10):CD009154.
- Wilding M, Di Matteo L, Dale B. The maternal age effect: a hypothesis based on oxidative phosphorylation.
Zygote 2005;13:317–23.
- Zayed F, Lenton EA, Cooke ID. Comparison between stimulated in-vitro fertilization and stimulated
intrauterine insemination for the treatment of unexplained and mild male factor infertility.
Hum Reprod. 1997 Nov;12(11):2408-13.
CAPITULO 11 – “O envelhecimento ovariano”
- Barad D, Gleicher N . Effect of dehydroepiandrosterone on oocyte and embryo yields, embryo
grade and cell number in IVF. Hum. Reprod. 2006 Nov;21(11):2845–9.
- Barad DH, Gleicher N. Increased oocyte production after treatment with dehydroepiandrosterone.
Fertil. Steril. 2005.Sep;84(3):756.
- Bentov Y, Esfandiari N, Burstein E, Casper RF. The use of mitochondrial nutrients to improve
the outcome of infertility treatment in older patients. Fertil Steril. 2010 Jan;93(1):272-5.
- Brann DW, Mahesh VB. The aging reproductive neuroendocrine axis. Steroids. 2005
- Check JH, Check ML, Katsoff D. Three pregnancies despite elevated serum FSH and advanced
age: case report. Hum. Reprod. 2000 Aug;15 (8): 1709–12.
- Check JH. Mild ovarian stimulation. J. Assist. Reprod. Genet. 2007 Dec;24(12):621–7.
- Check JH. Pharmacological options in resistant ovary syndrome and premature ovarian failure.
Clin Exp Obstet Gynecol 2006;33(2):71–7.
- Check ML, Check JH, Choe JK, Berger GS. Successful pregnancy in a 42-year-old woman with imminent
ovarian failure following ovulation induction with ethinyl estradiol without gonadotropins
and in vitro fertilization. Clin Exp Obstet Gynecol 2002;29(1): 11–4.
- Check ML, Check JH, Kaplan H. Pregnancy despite imminent ovarian failure and extremely high
endogenous gonadotropins and therapeutic strategies: case report and review. Clin Exp Obstet
Gynecol 2004;31(4):299–301.
- Cramer DW, Xu H, Harlow BL. Family history as a predictor of early menopause. Fertil Steril.
1995 Oct;64(4):740-5.
- Dragojević-Dikić S, Rakić S, Nikolić B, Popovac S. Hormone replacement therapy and successful
pregnancy in a patient with premature ovarian failure. Gynecol. Endocrinol. 2009

- Erol B, Bozlu M, Hanci V, Tokgoz H, Bektas S, Mungan G. Coenzyme Q10 treatment reduces
lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis
in a rat model of testicular ischemia/reperfusion injury. Fertil Steril. 2010 Jan;93(1):280-2.
- Fisch JD, Keskintepe L, Sher G. Gonadotropin-releasing hormone agonist/antagonist conversion
with estrogen priming in low responders with prior in vitro fertilization failure. Fertil. Steril.
2008 Feb;89(2):342–7.
- Gleicher N, Ryan E, Weghofer A, Blanco-Mejia S, Barad DH. Miscarriage rates after dehydroepiandrosterone
(DHEA) supplementation in women with diminished ovarian reserve: a case
control study. Reprod. Biol. Endocrinol. 2009 Oct 7;7:108.
- Katsoff B, Check JH. Successful pregnancy in a 45-year-old woman with elevated day 3 serum
follicle stimulating hormone and a short follicular phase. Clin Exp Obstet Gynecol
- Loutradis D, Drakakis P, Vomvolaki E, Antsaklis A. Different ovarian stimulation protocols for
women with diminished ovarian reserve. J. Assist. Reprod. Genet. 2007 Dec;24(12):597–611.
- Mamas L, Mamas E. Premature ovarian failure and dehydroepiandrosterone. Fertil. Steril.2009
- McKinlay SM, Brambilla DJ, Posner JG. The normal menopause transition. Maturitas. 1992
- Midgette AS, Baron JA. Cigarette smoking and the risk of natural menopause. Epidemiology.
1990 Nov;1(6):474-80.
- Santos TA, El Shourbagy S, St John JC. Mitochondrial content reflects oocyte variability and
fertilization outcome. Fertil Steril. 2006 Mar;85(3):584-91.
- Sauer MV, Paulson RJ, Lobo RA. Pregnancy in women 50 or more years of age: outcomes of 22
consecutively established pregnancies from oocyte donation. Fertil Steril.1995 Jul;64(1): 111–5.
- Snieder H, MacGregor AJ, Spector TD. Genes control the cessation of a woman›s reproductive
life: a twin study of hysterectomy and age at menopause. J Clin Endocrinol Metab. 1998
- Schurgers LJ, Vermeer C. Determination of phylloquinone and menaquinones in food. Effect of
food matrix on circulating vitamin K concentrations. Haemostasis. 2000 Nov-Dec;30(6):298-30.
- Souza AFM, Giugliani R. Doenças Mitocondriais. In: Carakushanski E. Doenças Genéticas em
Pediatria. Ed. Guanabara Koogan, RJ, 2001. Pp: 189-195.
- Tartagni M, Cicinelli E, De Pergola G, De Salvia MA, Lavopa C, Loverro G. Effects of pretreatment
with estrogens on ovarian stimulation with gonadotropins in women with premature
ovarian failure: a randomized, placebo-controlled trial. Fertil. Steril. 2007 Apr;87 (4): 858–61.
- Teran E, Hernandez I, Nieto B, Tavara R, Ocampo JE, Calle A. Coenzyme Q10 supplementation
during pregnancy reduces the risk of pre-eclampsia. Int J Gynaecol Obstet. 2009
- Torgerson DJ, Thomas RE, Campbell MK, Reid DM. Alcohol consumption and age of maternal
menopause are associated with menopause onset. Maturitas. 1997 Jan;26(1):21-5.
- Treloar SA, Do KA, Martin NG. Genetic influences on the age at menopause. Lancet. 1998 Oct
- Turi A, Giannubilo SR, Brugè F, Principi F, Battistoni S, Santoni F, Tranquilli AL, Littarru G,
Tiano L. Coenzyme Q10 content in follicular fluid and its relationship with oocyte fertilization
and embryo grading . Arch Gynecol Obstet. 2012 Apr;285(4):1173-6.
- Zhang J, Chang L, Sone Y, Silber S. Minimal ovarian stimulation (mini-IVF) for IVF utilizing
vitrification and cryopreserved embryo transfer. Reprod Biomed Online. 2010 Oct;21(4):485-95.

CAPITULO 12 – “Apoio emocional”
- Chavarro, J.;Willett, W.;Skerrett,P. (2007) The Fertility Diet McGraw-Hills Ed.
- Domar,A.D.; Conboy L.; Denardo-Roney, J.; Rooney, K.L.(2012) Lifestyle behaviores in women
undergoing in vitro fertilization: a prospective study. Fertility and Sterility (in press), copyright
American Society for Reproductive Medicine 2011.12.012
- Melamed, R.M.;Seger, L.; Borges,E.Jr. (2009) Psicologia e Reprodução Humana Assistida – Uma
Abordagem Multidisciplinar Gen Grupo Editorial Nacional.
CAPITULO 13 – “Alimentos que nutrem a fertilidade”
- ANVISA Portaria n º 29, de 13 de janeiro de 1998 (*)
- ANVISA “Manual de Orientação ao consumidor.”
- Food Standard Agency Organic review published Dangour, A. D., Lock, K., Hayter, A., Aikenhead,
A., Allen, E. & Uauy, R. (2010), Nutrition-related health effects of organic foods: a systematic
review. Am J ClinicalNutrition 92, 203-210, published online doi:10.3945/ajcn.2010.29269 29
July 2009
ICS: frequency of inclusion in the diet of artificial sweeteners especially aspartame,
sodium cyclamate and sodium saccharin - possible adverse effects. Danúzia Pacheco Natividade1
Denise Celeste
- Alimentos e Nutrição Araraquara, Vol. 18, No 1 (2007) Vol. 18, No 1 (2007) > DUTRA NITROSAMINAS
S. RATH, F. G. R. REYES; Livro “ O Futuro Roubado “Colborn/Myers Editora L&PM
- Hughes CL (Junho de 1988). “mimetismo fitoquímica de hormônios reprodutivos e modulação
da fertilidade herbívoro por fitoestrogênios” .Environ. SaúdePerspect. 78 : 171-4. DOI : 10.1289/
ehp.8878171 . PMC 1474615 . PMID 3203635
- Cooke PS, Buchanan DL, Palanza P, Thayer KA, Nagel SC, Parmigiani S, Welshons WV (1998).
“Uma abordagem de base fisiológica para o estudo de bisfenol A e outros produtos químicos
estrogênicos sobre o tamanho dos órgãos reprodutivos, a produção espermática diária e comportamento”.
ToxicolInd Saúde 14 (1-2):. 239-60 DOI : 10.1177/074823379801400115 .
- Rozati R, Reddy PP, P Reddanna, Mujtaba R (Dezembro de 2002). “O papel dos estrogênios
ambientais na deterioração da fertilidade fator masculino”. Fertil. Steril. 78 (6): 1187-94. DOI :
10.1016/S0015-0282 (02) 04.389-3 . PMID 12.477.510
- COM706. Comisión de las Comunidades Europeas. Estrategia comunitária em materia de alteradores
endocrinos(Sustancias de las que se sospecha interfieren em lo sistemas hormonales de
seres humanos y animales). Bruselas; 1999
- SACO 100EN. Endocrine disrupting chemicals: A challenge for the EU?. European Parliament,
Public Health and Consumer Protection Series, Strasburg, 1998.
- Ashford, N.; Miller, C.S. Low-Level Chemical Exposures:A Challenge for Science and Policy Environ.
Sci.Tech. 32: 508 A-509 A (1998)

- Pazos P, Olea-Serrano MF, Zuluaga A, Olea N. Endocrinedisruptingchemicals: Xenoestrogens.
Med Biol Environ Int J 1998; 26:41-
- Colborn T, vomSaal FS, Soto AM. Development effects of endocrine-disrupting chemicals in
wildlife and humans. Environ Health Perspect 1993; 101:378-84.
- Miller WR, Sharpe RM. Environmental oestrogens and human reproductive cancers. Endocrine-
related cancer 1998; 5:69-96.
- Adlercreutz H. Phytoestrogens: Epidemiology and a possible role in cancer protection. Environ
Health Perspect 1995; 03:103-12.
- Nikov GN, Hopkins NE, Boue S, Alworth WL. Interactions of dietary estrogens with human
estrogen receptors and the effect on estrogen receptor-estrogen response element complex formation.
Environ Health Perspect 2000; 108:867-72.
- Hadidi A.T., Azmy A. F., “Hypospadias surgery: An Illustrated Guide”; Library of Congress
Cataloging-in-Publication. Springer-Verlag, Berlin – Heidelberg, Germany. 2004
- Krimsky S. Hormonal chaos.The scientific and social origins of the environmental endocrine
hypothesis. Baltimore: Johns Hopkins University Press; 2000.
- Swan SH. Intrauterine exposure to diethylstilbestrol: long-term effects in humans. APMIS.
- Harris CA, Woolridge MW, Hay AWH. Factors affecting the transfer of organochlorine pesticides
residues to breastmilk.Chemosphere. 2001;43:243-56.
- Swan SH, Main KM, Liu F, Stewart SL, Kruse RL, Calafat AM, et al. Decrease in anogenital
distance among male infants with prenatal phthalate exposure. Environ Health Perspect.
- Kurahashi N, Kasai S, Shibata T, Kakizaki H, Nonomura K, Sata F, et al. Parental and neonatal
risk factors for cryptorchidism. Med SciMonit. 2005;11:274-83.
- De Kretser DM. Differences in the prevalence of cryptorchidism. Lancet.2003; 363:1250-1.
- Carpenter K, Zhao D. Forgotten mysteries in the early history of vitamin D. J Nutr 1999;129:923-
- Vieth R. Vitamin D nutrition and its potential health benefits for bone, cancer and other conditions.
J EnvNutr Med 2001;11:275-91.
- Neonatal Vitamin D Status and Risk of Schizophrenia A Population-Based Case-Control Study.
John J. McGrath, MD, PhD, FRANZCP; Darryl W. Eyles, PhD; Carsten B. Pedersen, MSc,
CAPITULO 15 – “Receitas que contribuem com a fertilidade”
- Lucchese F, Machado J A P. Dieta mediterrânea: com sabor brasileiro. L&PM, 7 ed. 2010.
- Oliveira, Flávio Garcia. Receitas para grávidas. Idéia e ação, 2008.
- Rossi, Roseli L. Saúde e Sabor com equilíbrio: receitas diet e light, Volume II. Clinica Equilíbrio
Nutricional Ltda., São Paulo. 2008, 1ª edição.
- Hark L, Deen D. A Dieta Milagrosa dos Grãos: perca peso e aumente a energia com uma alimentação
saudável. Publifolha, 2008.
- Nicola, Alessandro. Portal Mediterrâneo: o azeite nas culinárias espanhola e marroquina. LMA
Editora e Distribuidora Ltda, São Paulo, 2011. 1° edição.

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